Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Predialysis therapeutic care and health-related quality of life at dialysis onset (The pharmacoepidemiologic AVENIR study) | Boini et al. Health and Quality of Life Outcomes 2011 9 7 http content 9 1 7 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Predialysis therapeutic care and health-related quality of life at dialysis onset The pharmacoepidemiologic AVENIR study 3 Stephanie Boini 1 Luc Frimat Michele Kessler Serge Briangon 1 Nathalie Thilly 1 Abstract Background To determine the impact of the quality of pre-dialysis nephrological care on health-related quality of life HRQoL at dialysis onset which has not been well evaluated. Methods All adults who began a dialysis treatment in the administrative region of Lorraine France in 2005 or 2006 were enrolled in this prospective observational study. HRQoL was measured using the Kidney Disease Quality of Life V36 questionnaire which enables calculation of two generic physical and mental and three specific dimensions Symptoms problems Effects and Burden of kidney disease . The specific dimensions were scored from 0 to 100 worst to best possible functioning . Pre-dialysis nephrological care was measured using three indicators quality of therapeutic practices evaluated across five main aspects hypertension proteinuria anemia bone disease metabolic acidosis and dyslipidemia time since referral to a nephrologist and number of nephrology consultations in the year preceding dialysis treatment. Results Two thousand and eighty-three patients were referred to a nephrologist more than 1 month before dialysis initiation and completed the HRQoL questionnaire. Quality of therapeutic practices was significantly associated with the Mental component. Time since referral to a nephrologist was associated with Symptoms problems and the Effects of kidney disease dimensions but no relationship was found between the number of nephrology consultations and HRQoL. Conclusions HRQoL at dialysis onset is significantly influenced by the quality of pre-dialysis nephrological care. Therefore disease management should be .
