Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Five-year effect of community-based intervention Hartslag Limburg on quality of life: A longitudinal cohort study | Verkleij et al. Health and Quality of Life Outcomes 2011 9 11 http content 9 1 11 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Five-year effect of community-based intervention Hartslag Limburg on quality of life A longitudinal cohort study 1 1 23 2 Saskia PJ Verkleij Marcel C Adriaanse WM Monique Verschuren Eric C Ruland Gerrie CW Wendel-Vos Albertine J Schuit1 2 Abstract Background During the past decade quality of life QoL has become an accepted measure of disease impact therapeutic outcome and evaluation of interventions. So far very little is known about the effects of communitybased interventions on people s QoL. Therefore the effect of an integrative cardiovascular diseases communitybased intervention programme Hartslag Limburg on QoL after 5-years of intervention is studied. Methods A longitudinal cohort study comparing 5-year mean change in QoL between the intervention n 2356 and reference group n 758 . QoL outcomes were the physical and mental health composite scores PCS and MCS measured by the RAND-36. Analyses were stratified for gender and socio-economic status SES . Results After 5-years of intervention we found no difference in mean change in PCS and MCS between the intervention and reference group in both genders and low-SES. However for the moderate high SES intervention group the scales social functioning 95 CI to physical role limitations 95 CI to general mental health 95 CI to vitality 95 CI to and MCS 95 CI to significantly changed compared with the reference group. These differences were due to a slight decrease of QoL in the intervention group and an increase of QoL in the reference group. Conclusion Hartslag Limburg has no beneficial effect on people s physical and mental QoL after 5-years of intervention. In fact subjects in the intervention group with a moderate high SES show a decrease on their mental QoL compared with the reference group. .