Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Impact of childhood trauma on functionality and quality of life in HIV-infected women | Troeman et al. Health and Quality of Life Outcomes 2011 9 84 http content 9 1 84 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Impact of childhood trauma on functionality and quality of life in HIV-infected women 1 1 2 2 2 3 Zyrhea CE Troeman Georgina Spies Mariana Cherner Sarah L Archibald Christine Fennema-Notestine Rebecca J Theilmann3 Bruce Spottiswoode4 Dan J Stein5 6 and Soraya Seedat1 5 Abstract Background While there are many published studies on HIV and functional limitations there are few in the context of early abuse and its impact on functionality and Quality of Life QoL in HIV. Methods The present study focused on HIV in the context of childhood trauma and its impact on functionality and Quality of Life QoL by evaluating 85 HIV-positive 48 with childhood trauma and 37 without and 52 HIVnegative 21 with childhood trauma and 31 without South African women infected with Clade C HIV. QoL was assessed using the Quality of Life Enjoyment and Satisfaction Questionnaire Q-LES-Q the Patient s Assessment of Own Functioning Inventory PAOFI the Activities of Daily Living ADL scale and the Sheehan Disability Scale SDS . Furthermore participants were assessed using the Center for Epidemiologic Studies Depression Scale CES-D and the Childhood Trauma Questionnaire CTQ . Results Subjects had a mean age of years. After controlling for age level of education and CES-D scores analysis of covariance ANCOVA demonstrated significant individual effects of HIV status and childhood trauma on self-reported QoL. No significant interactional effects were evident. Functional limitation was however negatively correlated with CD4 lymphocyte count. Conclusions In assessing QoL in HIV-infected women we were able to demonstrate the impact of childhood trauma on functional limitations in HIV. Keywords HIV Quality of Life Childhood trauma Functionality Background South Africa is a country severely affected by the AIDS epidemic with one of the highest rates of
