Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Reliability and validity of a single item measure of quality of life scale for adult patients with cystic fibrosis | Yohannes et al. Health and Quality of Life Outcomes 2011 9 105 http content 9 1 105 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Reliability and validity of a single item measure of quality of life scale for adult patients with cystic fibrosis Abebaw M Yohannes1 Mary Dodd2 Julie Morris3 and Kevin Webb2 Abstract Background It is important to monitor health related quality of life in order to determine the efficacy of interventions and physical functioning of patients with cystic fibrosis in their daily activities. There is no a singleitem global quality of life scale for routine clinical practice for adult patients with cystic fibrosis. We assessed the reliability and validity of a single-item global quality of life scale and compared with the Cystic Fibrosis Quality of Life Questionnaire CF-QOL for adult patients with cystic fibrosis. Method 121 men 66 women 55 adult cystic fibrosis patients self-completed the CF-QOL the Hospital Anxiety Depression Scale and the single item global quality of life scale at the out patient clinic. 33 17 women completed the repeat questionnaires at home within two weeks. Socio-demographic characteristic and lung function data were extracted from the recent medical notes. Results Mean SD age was years and mean SD forced expiratory volume in 1 second was litres. The test-retest reproducibility using the intra-class correlation coefficient ICC for the CF-QOL was 95 confidence interval to . The single item global quality of life ICC score was 95 confidence interval to . Concurrent validity of the single-item global quality of life was examined in relation to all items of the CF-QOL frequent episodes of readmission anxiety and depression all p were moderately correlated. Conclusion The study provides preliminary evidence that the single-item quality of life scale is acceptable valid and repeatable for adult patients with cystic fibrosis. It is a promising tool .