Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up | Xie et al. Health and Quality of Life Outcomes 2010 8 87 http content 8 1 87 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Evaluation of health outcomes in osteoarthritis patients after total knee replacement a two-year follow-up I- - 3 24 Feng Xie Ngai-Nung Lo Eleanor M Pullenayegum Jean-Eric Tarride Daria J O Reilly Ron Goeree Hin-Peng Lee5 6 Abstract Objectives To quantify the improvement in health outcomes in patients after total knee replacement TKR . Methods This was a two-year non-randomized prospective observational study in knee osteoarthritis OA patients undergone TKR. Patients were interviewed one week before six months after and two years after surgery using a standardized questionnaire including the SF-36 the Oxford Knee Score OKS and the Knee Society Clinical Rating Scale KSS . A generalized estimating equation GEE model was used to estimate the magnitudes of the changes with and without the adjustment of age ethnicity BMI and years with OA. Results A total of 298 at baseline 176 at six-months and 111 at two-years eligible patients were included in the analyses. All the scores changed significantly over time with the exception of SF-36 social functioning vitality and mental health. With the adjustment of covariates the magnitude of changes in these scores was similar to those without the adjustment. Conclusions Both general and knee-specific physical functioning had been significantly improved after TKR while other health domains have not been substantially improved after the surgery. Introduction Osteoarthritis OA a chronic degenerative disease is characterized by pain and physical disability with knee being the most frequently affected joint 1 . OA is among the most prevalent diseases affecting adults and a major contributor to physical disability morbidity and utilization of health care resources worldwide 2-5 . In patients with severe knee OA who have failed conservative treatments . medications exercises
