Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài :Factors affecting the relationship between psychological status and quality of life in COPD patients | Balcells et al. Health and Quality of Life Outcomes 2010 8 108 http content 8 1 108 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Factors affecting the relationship between psychological status and quality of life in COPD patients Eva Balcells1 2 3 Joaquim Gea1 2 3 4 Jaume Ferrer3 5 Ignasi Serra2 6 Mauricio Orozco-Levi1 2 3 4 Jordi de Batlle2 6 7 c 1 f D I r I z t I I 73 5 2 6 7 Ch V 11 Ch s I u- o L . r -4 II . -72 6 I s- f- I . LZ . h I A L . 4 6 7 11 I zd I c. r T r r I A f m r r I r 2 4 6 7 Esther Rodríguez Marta Benet David Donaire-González Josep M Antó Judith Garcia-Aymerich the PAC-CoPd Study Group Abstract Background This study aims to i evaluate the association between anxiety and depressive symptoms and health-related quality of life HRQoL and ii identify the effect modifiers of this relationship in patients with chronic obstructive pulmonary disease COPD . Methods A total of 337 clinically stable COPD patients answered the St. George s Respiratory Questionnaire SGRQ assessing HRQoL and the Hospital Anxiety and Depression Scale HADS . Socio-demographic information lung function and other clinical data were collected. Results Most patients 93 were male they had a mean SD age of 68 9 years and mild to very severe COPD post-bronchodilator FEV1 52 16 predicted . Multivariate analyses showed that anxiety depression or both conditions were associated with poor HRQoL for all SGRQ domains . The association between anxiety and total HRQoL score was points higher indicating a worse HRQoL in current workers than in retired individuals. Estimates for patients with both anxiety and depression were points lower in stage I-II than in stage III-IV COPD and points higher in patients with other comorbidities than in those with only COPD. Conclusions This study shows a significant association between anxiety depression or both conditions and impaired HRQoL. Clinically relevant factors affecting the magnitude of this association .
