Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Prognostic utility of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) | Ilgen et al. International Journal of Emergency Medicine 2011 4 49 http content 4 1 49 o International Journal of Emergency Medicine a SpringerOpen Journal ORIGINAL RESEARCH Open Access Prognostic utility of the acute cardiac ischemia time-insensitive predictive instrument ACI-TIPI I u . s 1 . s u . c II .u k 1AI XZ E ly l Xt -klt -kl2 I I I I -xíí wx -xt -kt -k3 c l I 1 I zx4 E I I 7 X fz. I r - I ZX 75 E I I Ml I - I k I z t4 n V X Z Jonathan S Ilgen Alex F Manini uoo norrmann VICKI E Noble Ediza Giraldez Supapan Nualpring ano J Stephen Bohan5 Abstract Background We sought to evaluate the test characteristics of the acute cardiac ischemia time-insensitive predictive instrument ACI-TIPI in relation to 30-day major adverse cardiac events MACE among patients who presented to the Emergency Department with symptoms suggestive of an acute coronary syndrome. We then examined the test characteristics of various dichotomous ACI-TIPI cut points. Methods We prospectively recruited a cohort of Emergency Department ED patients with acute chest pain at two urban university hospitals between June and September 2006. Upon enrollment baseline demographics and cardiac risk factors were collected. An electrocardiogram ECG was performed and analyzed with the built-in ACI-TIPI multiple regression model software. An ACI-TIPI probability score was recorded for each patient. Diagnostic test characteristics of ACI-TIPI for MACE non-ST elevation myocardial infarction NSTEMI percutaneous coronary intervention coronary artery bypass grafting and all-cause mortality within 30 days were determined. Results Of 144 patients enrolled mean age years 59 men 19 13 patients suffered MACE within 30 days. Receiver-operating characteristics ROC for ACI-TIPI yielded a c-statistic of 95 CI p . An ACI-TIPI score of 20 had 100 sensitivity 95 CI 82-100 100 negative predictive value 95 CI 86-100 and 21 specificity 14-31 . Conclusions These preliminary results .
