Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Nanoparticles for Applications in Cellular Imaging | Nanoscale Res Lett 2007 2 430-441 DOI S11671-007-9081-5 NANO REVIEW Nanoparticles for Applications in Cellular Imaging K. Ted Thurn Eric M. B. Brown Aiguo Wu Stefan Vogt Barry Lai Jorg Maser Tatjana Paunesku Gayle E. Woloschak Received 28 May 2007 Accepted 18 July 2007 Published online 15 August 2007 to the authors 2007 Abstract In the following review we discuss several types of nanoparticles such as TiO2 quantum dots and gold nanoparticles and their impact on the ability to image biological components in fixed cells. The review also discusses factors influencing nanoparticle imaging and uptake in live cells in vitro. Due to their unique size-dependent properties nanoparticles offer numerous advantages over traditional dyes and proteins. For example the photostability narrow emission peak and ability to rationally modify both the size and surface chemistry of Quantum Dots allow for simultaneous analyses of multiple targets within the same cell. On the other hand the surface K. T. Thurn E. M. B. Brown A. Wu T. Paunesku G. E. Woloschak El Department of Radiation Oncology Northwestern University Robert E. Lurie Cancer Center Feinberg School of Medicine 303 E. Chicago Ave. Ward Building Room 13-007 Chicago IL 60611 USA e-mail g-woloschak@ S. Vogt B. Lai X-Ray Science Division Advanced Photon Source Argonne National Laboratory Argonne IL 60439 USA J. Maser Center for Nanoscale Materials Advanced Photon Source Argonne National Laboratory Argonne IL 60439 USA T. Paunesku G. E. Woloschak Department of Radiology Northwestern University Robert E. Lurie Cancer Center Feinberg School of Medicine 303 E. Chicago Ave. Ward Building Room 13-007 Chicago IL 60611 USA G. E. Woloschak Department of Cell and Molecular Biology Northwestern University Robert E. Lurie Cancer Center Feinberg School of Medicine 303 E. Chicago Ave. Ward Building Room 13-007 Chicago IL 60611 UsA characteristics of nanometer sized TiO2 allow efficient conjugation to nucleic acids which
