Examining specific problems—notably AIDS (Chap. 182), but also tuberculosis (TB, Chap. 158), malaria (Chap. 203), severe acute respiratory syndrome (SARS; Chap. 179), and key noncommunicable diseases—helps to sharpen the discussion of barriers to prevention, diagnosis, and care as well as means of overcoming them. We next discuss global health equity, drawing on notions of social justice that once were central to international public health but have fallen out of favor over the past several decades. .