Five years ago, Jennifer Lim, MD, and her expert colleagues published the first edition of Age-Related Macular Degeneration, a state-of-the-art summary of knowledge about this frequently blinding disease. In the Foreword to that edition, I noted that Dr. Lim had “fashioned this valuable compendium of the way things are—for now!” It is relevant to ask, therefore, if the state of the art and level of knowledge have progressed in the interval since then. Why indeed they have, and, in the vernacular of the day, they have evolved “big time!”.
