The closing years of the 19th century and the start of the 20th century witnessed the emergence of microbiology and immunology as discrete scientific disciplines, and in the work of Roux and Yersin, perhaps the first benefits of their synergy—immunotherapy against bacterial infection. As we advance into the new millennium, microbiology and immunology again offer a conceptual leap forward as antibody phage display gains increasing acceptance as the definitive technology for monoclonal production and unleashes new opportunities in immunotherapy, drug discovery, and functional genomics
