There are many excellent microbiology laboratory manuals on the market and many others that are called “in-house” productions because they are written for a microbiology course at a particular school. Why another microbiology manual? The answer is straightforward. Many instructors want a manual that is directly correlated with a specific textbook. As a result, this laboratory manual was designed and written to be used in conjunction with the textbook Microbiology, fifth edition, by Lansing M. Prescott, John P. Harley, and Donald A. Klein; however, it can be used with other textbooks with slight adaptation