Technology is a powerful force of change in our world. We live longer and arguably better lives than our great-great-grandparents because of advances in medical, communication, and transportation technology. As we enter this new century there is apparently no end in sight for the transformative potential of human innovation. However, there is now ample evidence that the real legacy of invention is defined in equal parts by its benefits to society as well as its costs. There is no technology that comes without some level of risk. What this can or should mean for the process of creating and nurturing emerging technology remains a central question for all.