Heart failure is the end stage of all diseases of the heart and is a major cause of morbidity and mortality. It is estimated to account for about 5% of admissions to hospital medical wards, with over 100 000 annual admissions in the United Kingdom. The overall prevalence of heart failure is 3 20 per 1000 population, although this exceeds 100 per 1000 in those aged 65 years and over. The annual incidence of heart failure is 1 5 per 1000, and the relative incidence doubles for each decade of life after the age of 45 years. The overall incidence is likely to increase in the future, because of both an.