The authors provided evidence regarding NSAIDs mechanism of action and NSAIDs management including low-dose aspirin therapy. The discovery of safe NSAIDs with reduced upper GI toxicity such as selective COX-2 inhibitors is also presented in this chapter. Vanaskova et al., described the functional disorders of the GIT, focusing on swallowing dysfunctions in human beings. It is well known that these disorders are not only difficult to verify and quantify but also difficult to treat. There are a great deal of problems associated with functional disorders related to psychosomatic, morphological and mechanical alterations as the real causative background for these diseases
