The purpose of writing this book was to overview recent hot topics in gastroenterology with a focus directed towards information derived from the bench and used at the patient's bedside. To address these issues, scientists who are working on a daily basis in the field of experimental gastroenterology and clinical investigators, with their chapter proposal's being peer-reviewed, all have integrated their attempts to summarize the recent advances in the pathophysiology and therapy of upper and lower gastrointestinal tract disorders