The second chapter case study by Rosso et al. presents a medical survey that tests professional drivers for the presence of various psychoactive substances. Positives were identified by using a commercially available immunoassay rapid kit test which indicates consumption of psychoactive drugs. This is of interest and important since the dependence on drugs may pose a risk to drivers in their profession affecting their reaction time and driving judgment. This is one of the first and important contributions to the literature in this area. The study is of high importance as drivers under the influence of psychoactive drugs may endanger themselves or others if impaired at the jobsite