It is essential to monitor intracranial pressure, CPP, and brain oxygenation during ventilatory support in the patients with traumatic brain injury. Brain oxygenation monitoring technics are jugular venous saturation monitoring, near-infrared spectroscopy and microdialysis catheters. Availability and cost of these devices are limiting factors to their use. The studies on brain trauma patients shows that there is no proven mortality benefit in continuous ICP monitoring.