Calling the family members, the relexing exercises, musical therapy, masaj and sitting exercises are important in control of anxiety and ajitation of patients. Safe and effective management of the pain and anxiety needs a delicate balance for analgesia and sedation protocols while managing delirium status. The weaning of patients from mechanical ventilation is often hampered by the sedation that they receive. Additionally, coordinated daily interruption of sedative infusions with objective re-titration in critically ill patients has been shown to decrease the durations of mechanical ventilation and length of ICU stay
