These disorders are caused by maturational white matter abnormalities and therefore white matter tractography (using DTI) can offer advantages over conventional MRI in the detectability of clinically relevant microstructural features. High field strength structural MR scanning (up to 7 tesla for clinical and research use in humans) is now available in some countries, and this greatly enhances the spatial resolution over that offered by standard clinical facilities (typically or 3 tesla). Similarly, better MRS spectral resolution is achieved at higher field strengths due to improved signal-tonoise and chemical-shift dispersion. The authors describe how developments in MR technology have provided clear clinical and practical benefits but also acknowledge their.
