Biomedical engineering is a discipline that is multidisciplinary by definition. The days when medicine was left to the physicians, and engineering was left to the engineers, seem to have passed us by. I have searched for an undergraduate/graduate level biomedical fluid mechanics textbook since I began teaching at Rose-Hulman in 1987. I looked for, but never found, a book that combined the physiology of the cardiovascular and pulmonary systems with engineering of fluid mechanics and hematology to my satisfaction, so I agreed to write a monograph. Ken McCombs at McGraw-Hill was satisfied well enough with that work that he asked me to write the textbook version that you see here