Work on Deisboeck and Kresh's Complex Systems Science in BioMedicine started years ago. In fact, thoughts and ideas leading up to this textbook date back to our first conversation, sometime in the fall of 1996. We quickly found common ground, and talked about emergence and self-organization and their relevance for medicine. We were both fascinated by the idea of complexity and marveled about its tremendous possibilities for cancer research, which was then and still is Tom's main scientific interest. Much has happened in science and technology since we first discussed our vision. For instance, in a remarkable international effort the human genome has been deciphered, nanotechnology has become a.
