Consequently, it is necessary to integrate the information of all the spectral images to classify tissues. Multi-spectral image processing techniques [1-3] are hence employed to collect spectral information for classification and of clinically critical values. In this paper, a new classification approach was proposed, it is called unsupervised Vector Seeded Region Growing (UVSRG). The UVSRG mainly select seed pixel vectors by means of standard deviation and relative Euclidean distance. Through the UVSRG processing, the data dimensionality of MRI can be decreased and the desired target of interest can be classified which the brain tissue and brain tumor segmentation. .