In under-resourced hematology laboratories there is usually a missing step in the battery of required investigations. Moreover, when some of the advanced diagnostic instruments can be found then the problem of chronic inadequate and irregular supply of kits and services would supervene. Therefore, the laboratory diagnosis would mostly depend on the more basic, but consistently available and well controlled, laboratory techniques that should at least include complete blood count (CBC) and peripheral blood morphology, after which a bone marrow study with aspirate and sometimes a trephine biopsy will follow. Moreover, in specialized hematology centers there may be a routine availability of few special stains, a very limited immunophenotyping.
