Although transperineal prostate biopsy with TRUS guidance was described in 1981 (Holm and Gammelgaard, 1981), more recent research has been undertaken on this previously used transperineal approach with the additional use of templates. This has facilitated control of the biopsy gun and allowed uniform sampling of the whole prostate. Furthermore there has been growing interest in the use of brachytherapy grid to take transperineal biopsies and therefore saturate the entire gland. Fewer complications have been reported with this technique and yet a greater detection rate of prostate cancer
