In the present analysis the main outcome measure was the incremental cost-utility ratio of using the detection of CPCs as opposed to serum PSA and/or abnormal digital rectal examination to indicate the need for a prostate biopsy, which calculated the saving or additional cost of implementing a screening program based on CPC. The analysis included direct medical costs of the biopsy, direct costs of adverse events (calculated from data obtained from a study conducted in the same hospital), an estimation of indirect costs in terms of lost income, were calculated as days of work lost/average Chilean wage per day as a percentage of the patient group in active.
