Complication rates were infection and severe hemorrhage. The total cost of the adverse effects was estimated by multiplying the number of biopsies by the frequency of adverse events. In men with a false positive test for PSA, an estimation of increased follow-up costs was made, this comprised of blood tests for PSA and free PSA and evaluation by the urologist every 4 months, and an estimated 8% of these patients underwent a second biopsy within one year of the first biopsy. In men with a false positive CPC detection, the hospital protocol is repetition of the CPC test with the PSA and free PSA at.
