Moreover it is important to be able to restrict this invasive investigation to men who are likely to benefit from treatment of this malignancy. There are currently concerns that Western clinicians and healthcare providers are over-diagnosing large numbers of men who would otherwise never have been troubled by their clinically undetectable prostate cancer. Moreover there are also concerns that large numbers of men are currently being over-treated for their prostate malignancy, resulting in treatment-related morbidity including surgical and radiotherapy complications such as erectile dysfunction and urinary incontinence. Over the last 25 years urologists and researchers have refined their skills sufficiently well to enable accurate diagnosis of a considerable.