It enables the patient to be fully engaged in this difficult decision making process. A negative consequence is the generation of a population of patients who may be described as the “worried well” . men with a slightly raised PSA who have either decided not to have a biopsy or who have had negative biopsies but who still have concerns that they might harbour prostate cancer. A number of pre-biopsy nomograms for prostate cancer risk assessment have been developed by a number of groups to predict the risk of prostate cancer on biopsy and its potential for progression. These risk calculators comprise predictive tables and nomograms and are.