Other adjustments include the incorporation of body mass index, the use of finasteride, percentage free PSA and [-2]pro-PSA. It should be noted that the results of the Cancer Risk Calculator for prostate cancer may not be applicable to all men as most participants in the PCPT were Caucasian, and results may not be applicable to men of other races. In addition, most men in this study underwent a sextant prostate biopsy. This has now been largely superseded by an increase in the number of systematic biopsies taken routinely (Heidenreich et al. 2010). Moreover, the risk calculator is only applicable to men aged 55 or older, without a.
