Regulation of female reproductive system consists of very complex interactions between the hypothalamus, neurohypophysis and ovaries. Beginning from the embryologic stage, female reproductive system is regulated by the brain. Ovarian hormone production is supressed by the hypothalamo-hypophyseal control mechanism till the end of the childhood period when the puberty begins. During puberty, menstrual cyclicity and timely ovulation, which are the result of the precise integration within different components of the reproductive system, are achieved. After puberty, comes the reproductive period which generally lasts about 30-35 years. During reproductive period, from daily social behavior to sexual life and reproduction, many important issues depend on normal ovarian folliculogenesis and hormonogenesis. Menopause.