Conventional treatments of hemorrhagic cystitis are hyper-hydration, diuresis and bladder irrigation to wash out viral particles and clots, and to prevent retrograde infection to kidneys and post-renal failure due to urethral obstruction caused by clots. High titer γ- globulin to specific adenovirus serotype is also administrated. In particular, serotype 35 specific antibody was present only at a very low titer in pooled gamma globulin (Flomenberg et al., 1987). Our group experienced sequential different serotype adenovirus infection of serotype 14 hemorrhagic cystitis and serotype 35 disseminated infection after cord blood transplantation, which is too confusing to treat because of the.