The currently available treatment options for glomerular disorders are not optimal since most of them either respond only partially or poorly so that relapse and progression is often the rule. Inadequate understanding of the factors underlying the development and progression of glomerular injury in various clinical scenarios is primarily responsible for lack of ideal therapies. The section on immune system and glomerulonephritis has three chapters which basically cover some of the actively investigated areas. Tetsuhiro Tanaka et al. discuss adaptive immune responses, both humoral and cell mediated in the context of Glomerulonephritis. Gian Marco Ghiggeri et al. wrote an exhaustive review on the immunological aspects of membranous nephropathy. Finally,.