The author also points out the exiting problems and obstacles in this field. In chapter seven, Adams et al. discuss how adenoviral vectors interact with human immune cells, particularly how adenoviral vectors interact with professional antigen presenting cells, namely dendritic cells. Chapter eight reviews the properties of the immune response induced by adenoviral vaccines and the mechanisms which control the quality of T cell response generated during such vaccination. Holst et al. compare the adenovirus vectors with other vaccination tools in the immunological arsenal, and discuss potential future clinical application of adenovirus vectored vaccines