The modular producer cell lines present several advantages: they are safer since integration of the vector within the packaging cell line was identified, the duration of the entire development process is much reduced as there is no need for screening and, in addition, production conditions are favorable due to the possibility of pre-adaptation of the master cell line to culture conditions and media. Thus, therapeutic virus production from bench to bedside becomes safer, faster, and cheaper (Coroadinha et al. 2010)
