The spleen is the intra-abdominal organ most often injured as a result of blunt trauma. The spleen is the most vascular organ of the body and, for this reason, splenic injury is potentially life threatening. The most common mechanism for such injury is motor vehicle collision. Left lower rib fractures are suggestive of spleen injury, although an intact rib cage does not exclude spleen trauma. The other trauma mechanisms are penetrating trauma stab, iatrogenic trauma following colonoscopy and spontaneous spleen rupture in some diseases that involve the spleen like infectious mononucleosis, hemopathies or metastasis. Nonsurgical management is becoming the preferred.