For the analysis of biological samples two blood samples were taken, one with 5 ml heparin for the determination of acetyl cholinesterase (AChE) and pseudo cholinesterase (PChE) by the technique of Michel and Aldrige (Vorhaus and Kark, 1953) and another of 5 ml without anticoagulant for the analysis of OC pesticides in serum. For this group 12 different pesticides (α-BHC, β-BHC, HCB, heptachlor, oxychlordane, α-chlordane, i-chlordane, α - endosulfan, β-endosulfan, 4,4-DDE, endosulfan and 2,4-DDT) were considered, which were determined by gas chromatography with electron micro capture (EPA, 1995) reporting the levels found