Of course, there is some truth in this answer, and probably much more than “some”. We are in the 21st century, and even animal experiments must be updated and modernized. I am perfectly convinced that preclinical scientists (among whom I proudly list myself) must learn, as they have done for a couple of centuries, new ways of designing and carrying out their experiments. “Blind” treatment and evaluation, use of older animals (more similar to stroke patients), reliance on permanent rather than on transient models of ischemia are just the simplest and most obvious improvements that should be implemented in the laboratory, at least for those experiments that are.
