The human genome is largely made of complex sequences evolved over time due to replication,mutations and insertion of foreign DNA. Based on the nucleotide distribution and functional significance, the genome has been categorized into different block of sequences, namely genes or coding and non-coding regions. A special type of sequence located near genes, in relation to spread of DNA methylation and dinucleotide frequencies are the CpG islands1. These islands are mostly found near the promoters, (5’end), of genes and their methylation levels are closely monitored to investigate the spread of Cancer. Useful insight on epigenetic mechanisms may be found from analysing the DNA sequence patterns or the genotype.
