Although this book is far from being exhaustive, it conveys some of the novel ideas and directions in the membrane trafficking field through a combination of review, research, and technical articles. The book is organized in a series of chapters that will “transport” the reader from the endoplasmic reticulum, where proteins and lipids are synthesized, to the plasma membrane, where molecules are either delivered or internalized via endocytosis. Some of the basic steps of the secretory pathway are here reviewed, such as the transport of cargo molecules from the ER to the Golgi apparatus, the sorting of transport intermediates at the Trans-Golgi Network, and the delivery of secretory.