Among halogens, fluorine is quite characteristic and specific since it has the largest electronegativity ( vs for oxygen) and the sterically second smallest van der Waals' radius ( ~ vs. for hydrogen). A carbon-fluorine bond is also stronger than a carbon-hydrogen bond (485 kJ/mol vs 414 kJ/mol). Therefore, fluoro organic compounds have unique chemical and physical properties. Recently, there has been increasing interest in the chemistry of fluoro organic compounds, which have wide application in various fields such as material science, medicinal, and theoretical chemistry. However, their preparation is not straightforward because ordinary synthetic methods are not always applicable to the preparation of fluorinated organic compounds
