In clinical practice left ventricular (LV) function is commonly evaluated by 2-D and M-mode echocardiography. These modalities have significant limitations,and tissue Doppler imaging (TDI) has been introduced as a quantitative and more objective method for assessing myocardial function. The TDI modalities include myocardial velocity imaging,displacement imaging,strain rate imaging, and strain imaging (Fig. 1). This review discusses the most recent developments in TDI-based cardiac diagnostics, and discusses how TDI may be applied in the evaluation of patients with acute myocardial infarction as well as chronic coronary artery disease