This book provides an interdisciplinary view of how to prepare the ecological and socio-economic systems to the reality of climate change. Scientifically sound tools are needed to predict its effects on regional, rather than global, scales, as it is the level at which socio-economic plans are designed and natural ecosystem reacts. The first section of this book describes a series of methods and models to downscale the global predictions of climate change, estimate its effects on biophysical systems and monitor the changes as they occur