For over 50 years, interest has been expressed in optimizing drug therapy through delivery system design. For many years this revolved around incorporating drugs into erodible or inert polymers, which then acted as platforms for controlled release, an approach that has been well reviewed in the literature. In more recent times there has been a move away from simply formulating drugs into erodible or inert polymers toward the design and development of more advanced drug delivery systems that utilize sophisticated designs and manufacturing techniques and rely on novel means for controlling the release of drug from the delivery system
