The advent of cancer therapy with the use of varous particle beams requires full understanding of radiation interactions with tumours and other materials for its optimal perfomance. Relevant knowledge in this respect comes from physics, chemistry, biology, medicine, and related technologies. A basic item of required Knowledge are the physical data that characterize the earliest phase of radiation interactions on the molecular level, which sets a stage for subsequent chemical and biological effects including the control of cancer. In view of the necessity of an interdisciplinary approach to full understanding, it is desirable to compile the physical data, to evaluate them for reliability, and to present them.