The field of molecular imaging/nuclear medicine continues to build excitement for the medical community as a whole. To be able to visualize fundamental molecular and biochemical processes in patients in a meaningful way has truly become reality. Of all the available molecular probes and tools it is clear that FDG with PET-CT is one of the true clinical success stories. Very few would have been able to predict the eventual impact of a simple glucose analog as a marker for imaging cancer, hibernating myocardium, Alzheimer’s disease, epilepsy and many other important disease processes