This book is the result of many years of clinical and academic interest in diffusion-weighted MR (DW) imaging of the brain. Researchers and clinicians at the University of Rochester started to collect DW images of a spectrum of abnormalities affecting the brain immediately after this technique became available. Several case series with clinical and radiographic correlations have been presented at the annual meetings of the American Society of Neuroradiology and the Radiological Society of North America via posters and scientific reports