The combination of functional metabolic information and anatomical data has been available since 2001, when the combined PET/CT scanner was introduced. This technology has had a significant impact on many medical disciplines, including cardiology and neurology, but undoubtedly the greatest impact has been in the field of oncological imaging. It is the ability of PET/CT to accurately identify the anatomical location of abnormal metabolic activity that has revolutionized the detection and staging of many tumors