With regard to submission, evaluation and selection procedures, both single-stage as well as two-stage submission and evaluation procedures will be used in separate calls. The relevant call is indicated for each topic in section II and the details for the procedures in separate call fiches in section III. It is particularly important that applicants address the potential ethical issues of their proposals, both in the proposed methodology and the possible implications of the results. The specific requirements for addressing ethical issues 24 are described in the Guide for Applicants (Annex 4, section 4). The differences of gender/sex in research.