In toxicology the effects are normally correlated to the quantity of product to which individual animals or humans are exposed. The greater the mass absorbed, the greater the effect. In the case of NP, it has been clearly shown that the measured effects are not linked to the mass of the product, which challenges our entire approach to the classical interpretation of toxicity measurement. It is clearly shown that at equal mass, NP are more toxic than products of the same chemical composition but of greater size. Although several studies find a good correlation between the specific surface.
